Identifying brain and behavior markers for bipolar disorder in youth

From Manic Symptoms to Bipolar Disorder: Neural-behavioral Markers Using Two Analytic Models

['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-11184809

This study is looking at young people who show early signs of bipolar disorder, like feeling really high or energetic, to find clues in their brain and behavior that might help doctors spot the condition sooner and provide better support.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-11184809 on ClinicalTrials.gov

What this research studies

This research investigates the early signs of bipolar disorder in adolescents by examining brain and behavioral markers. It focuses on youth who exhibit manic symptoms but have not yet been diagnosed with bipolar disorder. Using advanced analytic models, the study aims to identify neural patterns and behavioral indicators that could predict the development of bipolar disorder. By understanding these markers, the research seeks to improve early diagnosis and treatment options for affected youth.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents who display prodromal manic symptoms but have not yet been diagnosed with bipolar disorder.

Not a fit: Patients who do not exhibit any manic symptoms or have already been diagnosed with bipolar disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of bipolar disorder in youth, allowing for timely and effective interventions.

How similar studies have performed: Other research has shown promise in identifying biomarkers for psychiatric disorders, suggesting that this approach could yield valuable insights.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.