Identifying brain and behavior markers for bipolar disorder in youth
From Manic Symptoms to Bipolar Disorder: Neural-behavioral Markers Using Two Analytic Models
['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10793574
This study is looking at how early signs of mania in teenagers can help us understand who might develop bipolar disorder later on, using brain activity and behavior to find clues that could lead to better early diagnosis and treatment for those at risk.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10793574 on ClinicalTrials.gov |
What this research studies
This research investigates how early signs of manic symptoms in adolescents can predict the development of bipolar disorder. By examining brain activity and behavior in young patients, the study aims to identify specific neural and behavioral markers that indicate a higher risk for developing bipolar disorder. The researchers will use advanced analytic models, including machine learning techniques, to analyze data collected from youth during inpatient stays. This approach seeks to improve the accuracy of early diagnosis and treatment for those at risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12-20 who exhibit prodromal manic symptoms but have not yet been diagnosed with bipolar disorder.
Not a fit: Patients who are older than 20 or those who have already been diagnosed with bipolar disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of bipolar disorder in youth, allowing for timely and effective interventions.
How similar studies have performed: Other research has shown promise in using neural and behavioral markers to predict psychiatric outcomes, suggesting that this approach could be effective.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DILER, RASIM SOMER — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: DILER, RASIM SOMER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: bipolar affective disorder