Identifying blood markers for suicidal thoughts and behaviors in adolescents
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
['FUNDING_R01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-10877976
This study is looking at tiny particles in the blood that might help us find specific markers for understanding suicidal thoughts and behaviors in teenagers, with the hope of improving how we predict and support those at risk.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-10877976 on ClinicalTrials.gov |
What this research studies
This research investigates the use of neural-derived exosomes from blood plasma to identify microRNAs that may serve as biomarkers for suicidal ideation and attempts in adolescents. By analyzing these microRNAs, the study aims to uncover molecular pathways associated with suicide risk, which could lead to better prediction and treatment strategies. The approach involves isolating exosomes and examining their miRNA content to find patterns that differentiate adolescents at risk from those who are not. This could ultimately help in developing targeted interventions for at-risk youth.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents experiencing suicidal thoughts or behaviors.
Not a fit: Patients who are not adolescents or those without any history of suicidal ideation or attempts may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for predicting and preventing suicidality in adolescents.
How similar studies have performed: Previous research has shown promise in using microRNAs as biomarkers for various conditions, suggesting potential success for this novel approach.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DWIVEDI, YOGESH — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: DWIVEDI, YOGESH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.