Identifying blood markers for early lung cancer detection

Profiling genome-wide circulating ncRNAs for the early detection of lung cancer

NIH-funded research University of Hawaii at Manoa · NIH-10477044

This study is looking at blood samples to find tiny molecules that could help spot lung cancer earlier, especially for people at higher risk, so they can get the help they need sooner.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Hawaii at Manoa NIH-funded
Lab location1 site (Honolulu, United States)
Project IDNIH-10477044 on NIH RePORTER

What this research studies

This research aims to improve the early detection of lung cancer by profiling circulating non-coding RNAs (ncRNAs) found in blood samples. By analyzing these biomarkers, the study seeks to enhance the accuracy of lung cancer diagnosis, especially in high-risk patients who may benefit from earlier intervention. The approach involves collecting and examining blood samples from participants to identify specific ncRNA patterns associated with lung cancer. This could potentially lead to a non-invasive diagnostic tool that complements existing screening methods.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at high risk for lung cancer, such as smokers or those with a family history of the disease.

Not a fit: Patients who are not at high risk for lung cancer or those who have already been diagnosed with advanced lung cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase early detection rates of lung cancer, leading to improved survival outcomes for patients.

How similar studies have performed: Other studies have shown promise in using blood-based biomarkers for cancer detection, indicating that this approach could be a viable method for early lung cancer diagnosis.

Where this research is happening

Honolulu, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.