Identifying blood markers for early breast cancer detection in women with abnormal mammograms

Circulating lipid and miRNA markers for early detection of breast cancer among women with abnormal mammograms

NIH-funded research University of Hawaii at Manoa · NIH-10673061

This study is looking for ways to help women with abnormal mammogram results find out more easily whether they have breast cancer or not, by checking for certain markers in their blood, so they can avoid unnecessary and stressful follow-up procedures.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Hawaii at Manoa NIH-funded
Lab location1 site (Honolulu, United States)
Project IDNIH-10673061 on NIH RePORTER

What this research studies

This research focuses on improving the early detection of breast cancer among women who receive abnormal mammogram results. It aims to identify specific circulating lipid and miRNA markers in the blood that can help distinguish between benign conditions and early-stage breast cancer. By using these markers alongside mammography, the goal is to reduce the number of unnecessary follow-up procedures, such as biopsies, which can be costly and cause anxiety. The study builds on preliminary findings that suggest a high accuracy in differentiating between cancerous and non-cancerous conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have received abnormal mammogram results and are at risk for breast cancer.

Not a fit: Patients who have already been diagnosed with breast cancer or those who have normal mammogram results are unlikely to benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate breast cancer screenings, reducing unnecessary biopsies and associated stress for patients.

How similar studies have performed: Other research has shown promising results in using blood markers for cancer detection, indicating that this approach has potential for success.

Where this research is happening

Honolulu, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions American Cancer SocietyBreast CancerCancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.