Identifying blood markers for cognitive decline after COVID-19
Official title: Procoagulant platelets as biomarkers for post-COVID-19 cognitive decline
Funded at Oklahoma City VA Medical Center · NIH-11072997 · Data updated 2026-11-12
This study is looking at how specific blood platelets might help us understand the risk of memory and thinking problems in older adults, especially veterans, who have recovered from COVID-19, to find ways to prevent or treat these issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma City VA Medical Center NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | April 1, 2023 |
| Project end | September 30, 2027 |
| Funding year | 2025 |
| NIH project number | 5I01CX002578-03 |
| Project ID | NIH-11072997 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults, particularly those aged 65 and above, who have recovered from COVID-19 and are experiencing cognitive symptoms.
✕Less likely to help
Patients who are younger than 65 or have not had COVID-19 may not benefit from this research.
What this research studies
This research investigates how certain blood platelets may indicate the risk of cognitive decline in individuals who have recovered from COVID-19. It focuses on older adults, particularly veterans, who may experience cognitive impairment regardless of the severity of their initial COVID-19 infection. By analyzing the levels of procoagulant platelets, the study aims to uncover potential biomarkers that could help in preventing or treating cognitive issues following COVID-19. The approach includes examining blood samples and correlating platelet activity with cognitive assessments over time.
Why it matters
Potential benefit: If successful, this research could lead to early identification and targeted interventions for cognitive decline in post-COVID-19 patients.
How similar studies have gone: Previous research has shown promising results in identifying biomarkers related to cognitive decline in other populations, suggesting potential for success in this novel approach.
Where this research is happening
-
Oklahoma City VA Medical Center
Oklahoma City, United States Active
Researchers
- Principal investigator: Kirkpatrick, Angelia — Oklahoma City VA Medical Center
- Study coordinator: Kirkpatrick, Angelia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.