Identifying blood biomarkers for Alzheimer's disease risk based on sex differences
Sex-specific risk factors and trajectories of blood biomarkers for Alzheimer's disease and related dementias
['FUNDING_OTHER'] · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · NIH-10525327
This study is looking at how different factors for men and women might affect the chances of developing Alzheimer's and related dementias by checking blood markers, so we can help identify people at higher risk and offer them support before any symptoms appear.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HENNEPIN HEALTHCARE RESEARCH INSTITUTE (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10525327 on ClinicalTrials.gov |
What this research studies
This research investigates how sex-specific factors influence the risk of developing Alzheimer's disease and related dementias by examining blood biomarkers. The study aims to identify individuals at high risk for these conditions, allowing for timely preventative interventions. By analyzing data from older adults without diagnosed dementia, the research will explore how various characteristics, including comorbidities, affect the interpretation of these biomarkers. The goal is to create a personalized risk score that incorporates these findings to improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those without a current diagnosis of dementia, who may be at risk due to genetic or other factors.
Not a fit: Patients who are already diagnosed with Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of Alzheimer's disease risk and tailored prevention strategies for individuals.
How similar studies have performed: Previous research has shown promise in using blood biomarkers for Alzheimer's disease, but this approach focusing on sex differences is relatively novel.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- HENNEPIN HEALTHCARE RESEARCH INSTITUTE — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MURRAY, ANNE M — HENNEPIN HEALTHCARE RESEARCH INSTITUTE
- Study coordinator: MURRAY, ANNE M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.