Identifying blood-based biomarkers for Alzheimer's disease in diverse populations
Official title: Centrally-linked longitudinal peripheral biomarkers of AD in multi-ethnic populations
Funded at Mayo Clinic Jacksonville · NIH-11075357 · Data updated 2026-11-12
This study is looking for specific blood markers that can help diagnose Alzheimer's disease and understand how it affects different people, so if you or someone you know has Alzheimer's, this research could lead to better ways to track and manage the condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project start | March 15, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $8,409,935 |
| NIH project number | 5U19AG074879-03 |
| Project ID | NIH-11075357 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals from diverse ethnic backgrounds who are at risk for or diagnosed with Alzheimer's disease.
✕Less likely to help
Patients with early-stage Alzheimer's disease who do not belong to the targeted multi-ethnic populations may not receive direct benefits from this research.
What this research studies
This research focuses on discovering blood-based biomarkers for Alzheimer's disease (AD) that can reflect the complex biological changes associated with the condition. By analyzing various biological pathways and considering the diversity of populations, the study aims to identify specific molecular signatures that can aid in the diagnosis and understanding of AD. The research involves collaboration among over 40 experts across 13 institutions, utilizing advanced multi-omic approaches to capture the heterogeneity of AD and its co-existing conditions. Patients may be monitored over time to assess the effectiveness of these biomarkers in different ethnic groups.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and accessible diagnostic tools for Alzheimer's disease, particularly for underrepresented populations.
How similar studies have gone: Previous research has shown promise in identifying biomarkers for Alzheimer's disease, but this approach focusing on multi-ethnic populations is relatively novel.
Where this research is happening
-
Mayo Clinic Jacksonville
Jacksonville, United States Active
Researchers
- Principal investigator: Ertekin-Taner, Nilufer — Mayo Clinic Jacksonville
- Study coordinator: Ertekin-Taner, Nilufer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.