Identifying blood-based biomarkers for Alzheimer's disease
Official title: Discovering Centrally Linked Peripheral Molecular Signatures of Alzheimer's Disease
Funded at Mayo Clinic Jacksonville · NIH-11075366 · Data updated 2026-11-12
This study is looking for clues in the blood that could help doctors spot Alzheimer's disease early and keep track of it, so they can create better and more personalized treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project start | March 15, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,401,656 |
| NIH project number | 5U19AG074879-03 |
| Project ID | NIH-11075366 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or those at risk of developing it, particularly from diverse backgrounds including African American populations.
✕Less likely to help
Patients with other forms of dementia unrelated to Alzheimer's disease may not benefit from this research.
What this research studies
This research focuses on discovering blood-based biomarkers that can help in the early diagnosis and monitoring of Alzheimer's disease (AD). By analyzing both blood and brain samples from well-characterized patient cohorts, the study aims to identify molecular signatures that reflect changes in the brain associated with AD. The goal is to develop cost-effective and accessible diagnostic tools that can be used at the population level, ultimately leading to better patient stratification and personalized treatment options.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of Alzheimer's disease, improving treatment outcomes for patients.
How similar studies have gone: Previous studies have shown promise in identifying biomarkers for Alzheimer's disease, but this approach of linking blood and brain data is relatively novel.
Where this research is happening
-
Mayo Clinic Jacksonville
Jacksonville, United States Active
Researchers
- Principal investigator: Ertekin-Taner, Nilufer — Mayo Clinic Jacksonville
- Study coordinator: Ertekin-Taner, Nilufer
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.