Identifying biomarkers to predict treatment response in early psychosis
Pathophysiology Informed Biomarkers of Treatment Response in Early Psychosis (PIB)
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10828735
This study is looking at how we can better understand which young people with early psychosis will benefit from a special type of care, using brain scans to find patterns that help predict their response to treatment, so we can provide the best support for them right from the start.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10828735 on ClinicalTrials.gov |
What this research studies
This research investigates how to better predict which young individuals experiencing early psychosis will respond to Coordinated Specialty Care (CSC). By utilizing advanced neuroimaging techniques, such as fMRI and PET scans, the study aims to identify specific brain activity patterns and biomarkers that correlate with treatment outcomes. The goal is to enhance clinical decision-making by identifying non-responders early in their treatment journey, allowing for tailored interventions. This approach could significantly improve the effectiveness of care for individuals with early psychosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are young individuals who are experiencing the initial stages of a psychotic illness and are entering Coordinated Specialty Care.
Not a fit: Patients who are not experiencing early psychosis or those who are already receiving effective treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment plans for young individuals with early psychosis, improving their chances of recovery.
How similar studies have performed: Other research has shown promise in using neuroimaging to predict treatment outcomes in psychiatric conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CARTER, CAMERON S. — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: CARTER, CAMERON S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.