Identifying biomarkers to predict recovery outcomes after stroke
Validation of Early Prognostic Data for Recovery Outcomes after Stroke for Future, Higher Yield Trials (VERIFY)
This study is looking to find helpful signs that can predict how well stroke survivors will recover their arm and hand movement, so that doctors can tailor recovery plans to fit each person's needs, especially in the important early days after a stroke.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cincinnati NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11019809 on NIH RePORTER |
What this research studies
This research aims to validate biomarkers that can help predict recovery outcomes for stroke survivors, particularly focusing on upper extremity motor function. By using techniques like transcranial magnetic stimulation (TMS) and MRI, the study will assess the integrity of the corticomotor system and its impact on recovery. The goal is to identify biologically distinct patient subgroups to personalize recovery therapies, especially in the critical early days following a stroke. This validation process will involve a large-scale dataset to ensure the findings are robust and applicable to a wide range of patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently experienced an ischemic stroke and are experiencing upper extremity motor deficits.
Not a fit: Patients who have not had a stroke or those with non-ischemic stroke types may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective recovery therapies for stroke survivors, improving their chances of regaining motor function.
How similar studies have performed: Other research has shown promise in using biomarkers for predicting recovery outcomes in stroke patients, indicating that this approach has potential for success.
Where this research is happening
Cincinnati, United States
- University of Cincinnati — Cincinnati, United States (Active)
Researchers
- Principal investigator: Khatri, Pooja — University of Cincinnati
- Study coordinator: Khatri, Pooja
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.