Identifying biomarkers to predict disease severity and progression in Parkinson's disease
Official title: Biomarkers of disease severity and progression in Parkinson's
Funded at Portland VA Medical Center · NIH-11043304 · Data updated 2026-11-12
This study is looking at how specific biological markers can help us understand and predict how Parkinson's disease might progress in veterans, so we can provide better care and treatment options tailored just for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Portland VA Medical Center NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| NIH project number | 5IK2CX002539-03 |
| Project ID | NIH-11043304 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include veterans diagnosed with Parkinson's disease, especially those experiencing varying degrees of disease progression.
✕Less likely to help
Patients with Parkinson's disease who are not veterans or those with atypical forms of the disease may not benefit from this research.
What this research studies
This research investigates how certain biological markers can help predict the severity and progression of Parkinson's disease (PD), particularly in veterans who may be at higher risk due to military exposures. The study focuses on measuring mitochondrial function and using advanced imaging techniques to identify patterns that correlate with disease progression. By understanding these biomarkers, the research aims to improve patient counseling and enhance the design of clinical trials for new treatments. This approach could lead to more personalized care for patients with PD.
Why it matters
Potential benefit: If successful, this research could provide critical insights that help tailor treatment plans and improve quality of life for patients with Parkinson's disease.
How similar studies have gone: While the approach of using biomarkers to predict disease progression is promising, this specific methodology is relatively novel and has not been extensively tested in Parkinson's disease.
Where this research is happening
-
Portland VA Medical Center
Portland, United States Active
Researchers
- Principal investigator: Neilson, Lee — Portland VA Medical Center
- Study coordinator: Neilson, Lee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.