Identifying biomarkers to predict chronic pain from acute pain
Clinical Coordinating Center for the Acute to Chronic Pain Signatures Program
This study is looking at how some people go from having short-term pain to long-lasting pain, and it aims to find clues that can help doctors create better, personalized treatments for acute pain, which could help reduce the use of opioids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project ID | NIH-10685787 on NIH RePORTER |
What this research studies
This research focuses on understanding how some individuals transition from experiencing acute pain to developing chronic pain. By identifying specific biomarkers that indicate a person's risk for this transition, the study aims to personalize treatment strategies for acute pain, potentially reducing the need for opioids. The research involves a large consortium of pain scientists and utilizes multisite observational studies to gather comprehensive data across various factors that influence pain. Patients may be monitored and assessed to determine their pain responses and biological markers.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have recently experienced acute pain and are at risk of developing chronic pain.
Not a fit: Patients who have chronic pain conditions already established may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective pain management strategies and reduce the incidence of chronic pain in patients.
How similar studies have performed: Previous research has shown promise in identifying biomarkers related to pain, but this approach aims to advance the field further by focusing specifically on the transition from acute to chronic pain.
Where this research is happening
Iowa City, United States
- University of Iowa — Iowa City, United States (Active)
Researchers
- Principal investigator: Sluka, Kathleen a — University of Iowa
- Study coordinator: Sluka, Kathleen a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.