Identifying biomarkers to predict chronic pain after acute pain events

Clinical Coordinating Center for the Acute to Chronic Pain Signatures Program

NIH-funded research University of Iowa · NIH-10690109

This study is looking at why some people with short-term pain end up with long-lasting pain, and it aims to find ways to tailor treatments for them, which could help reduce the use of opioids.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Iowa NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-10690109 on NIH RePORTER

What this research studies

This research focuses on understanding how some individuals transition from experiencing acute pain to developing chronic pain. By identifying specific biomarkers that indicate a person's risk or resilience to this transition, the study aims to personalize treatment strategies for acute pain, potentially reducing the need for opioids. The research involves a large consortium of pain scientists and utilizes multisite observational studies to gather comprehensive data across various factors affecting pain. Patients may be monitored and assessed to help develop effective pain management strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have recently experienced acute pain and are at risk of developing chronic pain.

Not a fit: Patients who do not experience acute pain or have pre-existing chronic pain conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized pain management strategies, reducing the incidence of chronic pain and reliance on opioids.

How similar studies have performed: Other research has shown promise in identifying biomarkers for pain management, suggesting that this approach could yield significant insights.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.