Identifying biomarkers to predict brain damage after traumatic injuries
BCCMA: Predicting TBI Pathology with Visual and Blood-based Biomarkers
This study is looking for signs in the eyes and blood that can help predict long-term brain problems after a head injury, and it's especially for veterans who have experienced traumatic brain injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10951516 on NIH RePORTER |
What this research studies
This research aims to find reliable biomarkers that can predict long-term brain dysfunction following traumatic brain injury (TBI). The study will explore how changes in the retina and specific blood markers can indicate neurodegeneration in the brain after an injury. It will involve multiple phases, starting with the discovery of these biomarkers through various assessments, including brain imaging and cognitive tests. The research will also validate these biomarkers using samples from both animal models and human participants, particularly veterans.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced traumatic brain injuries, particularly veterans.
Not a fit: Patients who have not suffered a traumatic brain injury or those with pre-existing neurological conditions unrelated to TBI may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools for predicting and managing chronic brain damage in TBI patients.
How similar studies have performed: Previous research has shown promise in using biomarkers for brain injury assessment, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- Veterans Affairs Med Ctr San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Ferguson, Adam R — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Ferguson, Adam R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.