Identifying biomarkers to improve recovery after cardiac arrest
PREcision Care In Cardiac ArrEst - ICECAP (PRECICECAP)
This study is looking for ways to better understand how patients who have had a cardiac arrest and brain injuries respond to treatments, so we can improve their recovery and survival by finding the best cooling therapy for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11086610 on NIH RePORTER |
What this research studies
This research aims to discover new biomarker signatures that can predict how well patients will respond to treatments after experiencing cardiac arrest and related brain injuries. By collaborating with the ICECAP trial, the study will explore the optimal duration of cooling therapy post-arrest, which is crucial for patient recovery. The approach involves advanced data analysis to identify different patient responses and tailor treatments accordingly, addressing significant gaps in current clinical practices. The goal is to enhance survival rates and functional recovery for patients affected by cardiac arrest.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a cardiac arrest and are undergoing treatment for associated brain injuries.
Not a fit: Patients who have not experienced cardiac arrest or those with chronic, non-acute neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients recovering from cardiac arrest.
How similar studies have performed: Previous research has shown promise in using biomarker signatures to predict treatment outcomes in similar acute conditions, indicating potential for success in this novel approach.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Hirsch, Karen G — Stanford University
- Study coordinator: Hirsch, Karen G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.