Identifying biomarkers to improve prostate cancer treatment decisions

BCC for Prostate Cancer: Discovery and Translation of Biomarkers for Clinical Unmet Needs

NIH-funded research Johns Hopkins University · NIH-10890722

This study is looking to help men with low-risk prostate cancer by creating a new test that combines different markers into one score, making it easier for doctors to decide who really needs treatment and who can safely wait, so they can avoid unnecessary procedures.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10890722 on NIH RePORTER

What this research studies

This research focuses on improving the management of low-risk prostate cancer patients through active surveillance. It aims to develop and validate diagnostic tests that combine multiple biomarkers into a single score, helping doctors accurately assess the aggressiveness of the cancer and determine the best treatment approach. By enhancing the ability to identify true low-risk patients, the research seeks to reduce unnecessary treatments and biopsies while ensuring that those who need more aggressive intervention receive it in a timely manner.

Who could benefit from this research

Good fit: Ideal candidates for this research are men diagnosed with low-risk prostate cancer who are considering active surveillance as a treatment option.

Not a fit: Patients with high-risk prostate cancer or those who are not candidates for active surveillance may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate treatment decisions for prostate cancer patients, minimizing overtreatment and undertreatment.

How similar studies have performed: Previous research has shown promise in using biomarker panels for cancer assessment, indicating potential success for this approach.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.