Identifying biomarkers to improve prostate cancer treatment decisions
Official title: BCC for Prostate Cancer: Discovery and Translation of Biomarkers for Clinical Unmet Needs
Funded at Johns Hopkins University · NIH-10890722 · Data updated 2026-11-12
This study is looking to help men with low-risk prostate cancer by creating a new test that combines different markers into one score, making it easier for doctors to decide who really needs treatment and who can safely wait, so they can avoid unnecessary procedures.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 20, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $936,098 |
| NIH project number | 5U2CCA271895-02 |
| Project ID | NIH-10890722 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men diagnosed with low-risk prostate cancer who are considering active surveillance as a treatment option.
✕Less likely to help
Patients with high-risk prostate cancer or those who are not candidates for active surveillance may not benefit from this research.
What this research studies
This research focuses on improving the management of low-risk prostate cancer patients through active surveillance. It aims to develop and validate diagnostic tests that combine multiple biomarkers into a single score, helping doctors accurately assess the aggressiveness of the cancer and determine the best treatment approach. By enhancing the ability to identify true low-risk patients, the research seeks to reduce unnecessary treatments and biopsies while ensuring that those who need more aggressive intervention receive it in a timely manner.
Why it matters
Potential benefit: If successful, this research could lead to more accurate treatment decisions for prostate cancer patients, minimizing overtreatment and undertreatment.
How similar studies have gone: Previous research has shown promise in using biomarker panels for cancer assessment, indicating potential success for this approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Chan, Daniel Wanyui — Johns Hopkins University
- Study coordinator: Chan, Daniel Wanyui
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.