Identifying biomarkers to assess severity of COVID-19 in children
Discovery and clinical validation of host biomarkers of disease severity and multi-system inflammatory syndrome in children (MIS-C) with Covid-19
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10733698
This study is looking to create better tests to help doctors understand how serious COVID-19 is in kids, especially those with a condition called MIS-C, by analyzing samples from young patients to find clues that can guide their treatment.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10733698 on ClinicalTrials.gov |
What this research studies
This research aims to develop clinical tests that can accurately diagnose and predict the severity of COVID-19 in children, including those with multisystem inflammatory syndrome (MIS-C). By collecting and analyzing clinical samples from pediatric patients, the study will utilize advanced techniques such as machine learning and RNA profiling to identify specific biomarkers associated with disease severity. The goal is to create predictive models that can help healthcare providers make informed decisions about treatment and management of COVID-19 in young patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-21 who have been diagnosed with COVID-19 or exhibit symptoms related to MIS-C.
Not a fit: Patients who are not affected by COVID-19 or MIS-C may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for children affected by COVID-19 and MIS-C.
How similar studies have performed: Previous research has shown promise in using biomarker identification for other diseases, suggesting potential success for this novel approach in pediatric COVID-19.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHIU, CHARLES YEN — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: CHIU, CHARLES YEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.