Identifying biomarkers linked to the DASH diet and its effects on blood pressure
Discovery, Replication, and Validation of Biomarkers of the DASH Diet and Hypertension
This study is looking at how following the DASH diet, which focuses on eating more fruits, vegetables, and low-fat dairy while cutting back on salt and unhealthy fats, can help lower blood pressure and improve heart health, and it’s for anyone interested in understanding how this diet works for different people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10903730 on NIH RePORTER |
What this research studies
This research investigates how the DASH diet, which emphasizes fruits, vegetables, and low-fat dairy while reducing sodium and saturated fats, can influence blood pressure and overall cardiovascular health. By utilizing advanced techniques like metabolomics and proteomics, the study aims to discover new biomarkers that reflect adherence to the DASH diet and its effectiveness in lowering blood pressure. The research will involve analyzing biological samples from diverse populations to validate these biomarkers and understand their role in dietary patterns and health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are interested in dietary interventions for hypertension management.
Not a fit: Patients who do not have hypertension or are not interested in dietary changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better dietary recommendations and personalized nutrition strategies for managing hypertension and cardiovascular disease.
How similar studies have performed: Previous research has shown promise in using metabolomics and proteomics to identify dietary biomarkers, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Rebholz, Casey Marie — Johns Hopkins University
- Study coordinator: Rebholz, Casey Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.