Identifying biomarkers for the transition from acute to chronic pain

Clinical Coordinating Center for the Acute to Chronic Pain Signatures Program

NIH-funded research University of Iowa · NIH-10441496

This study is looking at how specific biological signs can help us understand who might develop chronic pain after having acute pain, so we can create better, personalized treatment plans that help manage pain without relying on opioids.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Iowa NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-10441496 on NIH RePORTER

What this research studies

This research investigates how certain biological markers can predict whether individuals will develop chronic pain after experiencing acute pain. By analyzing data from a large group of participants, the study aims to create personalized treatment strategies that reduce the need for opioids and improve pain management. The research involves collaboration among pain scientists and data management experts to ensure rigorous analysis and effective outcomes. Patients may be monitored for their pain responses and biological indicators to better understand their pain profiles.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have recently experienced acute pain and are at risk of developing chronic pain.

Not a fit: Patients who do not have acute pain or those with pre-existing chronic pain conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective pain management strategies and reduce the reliance on opioid medications for patients.

How similar studies have performed: Previous research has shown promise in identifying biomarkers for pain management, suggesting that this approach could lead to significant advancements in the field.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.