Identifying biomarkers for the risk and progression of Type 1 diabetes
The KQ1 serum study: soluble biomarkers for T1D risk, development & progression
This study is looking for clues in blood samples to help us understand what causes Type 1 diabetes and how it changes over time, so if you're at risk for T1D, your participation could help improve prevention and treatment strategies for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11018609 on NIH RePORTER |
What this research studies
This research focuses on understanding the risk factors and progression of Type 1 diabetes (T1D) by identifying and validating novel biomarkers in blood samples. It involves a nested case/control study of individuals at risk for T1D, where researchers will analyze the immune responses and genetic factors that contribute to the disease. By tracking these biomarkers over three years, the study aims to provide insights into the natural history of T1D and improve strategies for prevention and intervention. Patients participating will contribute to a better understanding of how T1D develops and progresses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk for Type 1 diabetes, particularly those with multiple autoantibodies.
Not a fit: Patients who do not have any risk factors for Type 1 diabetes or who are already diagnosed with the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for predicting and preventing Type 1 diabetes in at-risk individuals.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for autoimmune diseases, suggesting that this approach could yield valuable insights for Type 1 diabetes as well.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Homann, Dirk — Icahn School of Medicine at Mount Sinai
- Study coordinator: Homann, Dirk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.