Identifying biomarkers for rapid progression of idiopathic pulmonary fibrosis
Developing an exosomic signature of rapidly progressive idiopathic pulmonary fibrosis
This study is looking at blood samples from people with rapidly progressing idiopathic pulmonary fibrosis (IPF) to find specific markers that could help doctors detect and treat the disease earlier, making it easier for patients to manage their condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11054916 on NIH RePORTER |
What this research studies
This research focuses on idiopathic pulmonary fibrosis (IPF), a serious lung disease that can progress rapidly in some patients, leading to severe respiratory failure. The study aims to identify unique signatures of extracellular vesicle microRNAs (EV-miRNAs) in the blood of patients with rapidly progressive IPF. By analyzing these biomarkers, the researchers hope to improve early detection and treatment strategies for patients at risk of rapid disease progression. The approach involves collecting blood samples and conducting detailed analyses to uncover potential targets for intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with idiopathic pulmonary fibrosis, particularly those experiencing rapid disease progression.
Not a fit: Patients with stable or slowly progressing idiopathic pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and treatment of patients with rapidly progressive IPF, potentially improving their outcomes and quality of life.
How similar studies have performed: Previous studies have shown promise in using extracellular vesicle microRNAs as biomarkers in other conditions, suggesting potential success in this novel approach for IPF.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Eckhardt, Christina M — Columbia University Health Sciences
- Study coordinator: Eckhardt, Christina M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.