Identifying biomarkers for oropharyngeal cancer treatment outcomes
Multimodal Biomarkers For Oropharyngeal Cancer
This study is looking to help patients with oropharyngeal cancer by finding better ways to predict how well their treatment will work, using information about HPV and other markers, so that doctors can create more personalized treatment plans just for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10799539 on NIH RePORTER |
What this research studies
This research focuses on improving the prediction of treatment outcomes for patients with oropharyngeal squamous cell carcinoma (OPSCC), a type of head and neck cancer. By investigating the role of human papillomavirus (HPV) and other clinical biomarkers, the study aims to develop more accurate methods for stratifying patients based on their risk of disease progression and survival. The approach includes analyzing microRNAs and their impact on tumor response to standard cancer therapies. This could lead to more personalized treatment plans for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with oropharyngeal squamous cell carcinoma, particularly those with HPV-positive and HPV-negative tumors.
Not a fit: Patients with other types of head and neck cancers or those without a diagnosis of oropharyngeal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored treatment strategies for patients with oropharyngeal cancer.
How similar studies have performed: Previous studies have shown promise in using clinical biomarkers for prognostic purposes in head and neck cancers, indicating that this approach has potential for success.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Li, Hua — Washington University
- Study coordinator: Li, Hua
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.