Identifying biomarkers for early detection of osteoarthritis
Metabolomic Profiling to Identify Candidate Biomarker Profiles and Molecular Endotypes for Osteoarthritis
This study is looking at how certain substances in your body can help spot osteoarthritis early, which could lead to better treatment and care for the millions of people living with this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Montana State University - Bozeman NIH-funded |
| Lab location | 1 site (Bozeman, United States) |
| Project ID | NIH-10904870 on NIH RePORTER |
What this research studies
This research investigates the use of metabolomic profiling to identify potential biomarkers for osteoarthritis (OA), a condition affecting over 50 million people in the US. By analyzing the metabolites present in synovial fluid and plasma, the study aims to uncover biological markers that could facilitate early detection of OA, which is crucial for timely intervention and management. The approach focuses on understanding the metabolic changes associated with OA, potentially leading to improved clinical care and outcomes for patients. The research employs advanced biochemical analyses to characterize these metabolic profiles and their relationship to disease progression.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for osteoarthritis or those experiencing early symptoms of joint pain and dysfunction.
Not a fit: Patients with advanced osteoarthritis or those who do not exhibit any symptoms related to joint pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of FDA-approved biomarkers that enable early detection and intervention for osteoarthritis, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using metabolomic profiling for other conditions, suggesting that this innovative approach may yield valuable insights for osteoarthritis as well.
Where this research is happening
Bozeman, United States
- Montana State University - Bozeman — Bozeman, United States (Active)
Researchers
- Principal investigator: June, Ronald Kent — Montana State University - Bozeman
- Study coordinator: June, Ronald Kent
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.