NIH-funded research R01 grant

Identifying biomarkers for different types of lower urinary tract symptoms and their treatment responses

Official title: Identification of biomarker signatures of subtypes of LUTS and their response to treatments using samples from LURN study

Funded at Arbor Research Collaborative for Health · NIH-10413153 · Data updated 2026-11-12

This study is looking at how certain markers in your blood can help doctors better understand and treat different types of lower urinary tract symptoms (LUTS), using samples from a large group of people to find out what works best for you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionArbor Research Collaborative for Health
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startAugust 1, 2020
Project endJune 30, 2025
Funding year2022
Award (this year)$213,678
NIH project number5R01DK125251-03
Project IDNIH-10413153 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include men and women experiencing lower urinary tract symptoms, particularly those who have undergone treatment.

Less likely to help

Patients with LUTS who are not seeking treatment or those with unrelated urinary conditions may not benefit from this research.

What this research studies

This research investigates lower urinary tract symptoms (LUTS) by analyzing blood samples to identify specific biomarkers that can differentiate between various subtypes of LUTS. By utilizing over 75,000 biosamples collected from the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN), the study aims to uncover how these biomarkers relate to treatment responses. The goal is to improve the understanding of LUTS and enhance clinical management by providing tools that can accurately classify and predict patient outcomes based on their biomarker profiles.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients suffering from LUTS.

How similar studies have gone: Previous research has shown promise in identifying biomarkers for LUTS, but this study aims to address existing gaps and improve upon those findings.

Where this research is happening

  • Arbor Research Collaborative for Health
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Andreev, Victor P. — Arbor Research Collaborative for Health
  • Study coordinator: Andreev, Victor P.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.