Identifying biomarkers for cervical cancer screening in women with HIV in low-income countries
Global Hypomethylation Biomarkers for Cervical Cancer Screening in Women Living with HIV in LMICs
This study is looking to create a simple and affordable way to screen for cervical cancer in women with HIV living in low and middle-income countries, helping to catch the disease early and improve their health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10472739 on NIH RePORTER |
What this research studies
This research focuses on developing a new, non-invasive screening method for cervical cancer specifically for women living with HIV in low and middle-income countries (LMICs). It aims to understand how HIV infection contributes to cervical cancer by studying changes in DNA methylation patterns. By identifying specific biomarkers associated with cervical cancer, the project seeks to create a more accessible and cost-effective screening tool that can be used in regions where traditional methods are not feasible. This approach could significantly improve early detection and prevention of cervical cancer in vulnerable populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are women living with HIV in low and middle-income countries, particularly those at risk for cervical cancer.
Not a fit: Patients who do not live in low and middle-income countries or who are not HIV-positive may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cervical cancer screening methods that are more accessible and effective for women living with HIV.
How similar studies have performed: Other research has shown promise in using epigenetic markers for cancer detection, indicating that this approach could be viable.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Zheng, Yinan — Northwestern University at Chicago
- Study coordinator: Zheng, Yinan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.