Identifying biomarkers for brain vascular disorders that cause bleeding
Biomarkers of Cerebral Cavernous Angioma with Symptomatic Hemorrhage (CASH)
This study is looking for clues in the blood that can help doctors better diagnose and manage cerebral cavernous angioma, especially for patients who have recently had a brain bleed, so they can get the best care possible.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10839828 on NIH RePORTER |
What this research studies
This research focuses on cerebral cavernous angioma (CA), a condition that affects blood vessels in the brain and can lead to serious bleeding. The study aims to identify specific biomarkers in the blood that can help diagnose this condition, predict the risk of future bleeding, and monitor patients after a hemorrhage. By analyzing genetic mechanisms and other biological factors, researchers hope to improve the accuracy of diagnosis and treatment options for affected individuals. Patients who have experienced a recent brain hemorrhage will be the primary focus of this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with cerebral cavernous angioma and have experienced a recent symptomatic hemorrhage.
Not a fit: Patients who do not have cerebral cavernous angioma or have not experienced a recent hemorrhage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for patients at risk of recurrent brain hemorrhages.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for similar vascular conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Awad, Issam a — University of Chicago
- Study coordinator: Awad, Issam a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.