Identifying biomarkers for brain health and cognitive decline in aging and Alzheimer's disease
Project 3: Precision biomarkers of Brain Health, Age-related Cognitive Impairment and AD
This study is looking at certain markers in the fluid around your brain to see how they relate to brain health and thinking skills as we get older, especially in people with mild cognitive impairment or Alzheimer's, to help improve understanding and care for these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10906888 on NIH RePORTER |
What this research studies
This research investigates specific biomarkers in cerebrospinal fluid (CSF) that are linked to brain health and cognitive function as people age. It focuses on three key biochemical pathways that are believed to influence cognitive resilience and longevity. By analyzing these pathways, the research aims to understand how they are affected in conditions like mild cognitive impairment and Alzheimer's disease. Patients may undergo assessments to evaluate these biomarkers, which could lead to better understanding and management of cognitive decline.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults experiencing age-related cognitive decline or those diagnosed with mild cognitive impairment or Alzheimer's disease.
Not a fit: Patients who are not experiencing cognitive decline or do not have a diagnosis related to Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatments for age-related cognitive impairments and Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in identifying biomarkers related to cognitive health, making this approach a continuation of ongoing efforts in the field.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Worley, Paul F — University of Arizona
- Study coordinator: Worley, Paul F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.