Identifying biomarkers for Alzheimer's disease in adults with Down syndrome
Project 3: Biomarkers for DS Clinical Trials
This study is looking for ways to better understand and treat Alzheimer's disease in adults with Down syndrome by finding specific biological markers that can help personalize their treatment, and it involves various health checks and tests to gather important information.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10667611 on NIH RePORTER |
What this research studies
This research focuses on developing biomarkers to improve clinical trials for Alzheimer's disease specifically in adults with Down syndrome. It aims to create a precision medicine model that tailors treatments based on individual biological markers. Participants will undergo thorough assessments, including medical evaluations, neuropsychological tests, and advanced imaging techniques. The goal is to enhance understanding and treatment options for Alzheimer's disease in this unique population.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with Down syndrome who are at risk of developing Alzheimer's disease.
Not a fit: Patients without Down syndrome or those who are not at risk for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for Alzheimer's disease in adults with Down syndrome.
How similar studies have performed: Previous research has shown promise in developing biomarkers for neurodegenerative diseases, indicating potential success for this novel approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: O'bryant, Sid E — University of Pittsburgh at Pittsburgh
- Study coordinator: O'bryant, Sid E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.