Identifying biomarkers for aggressive prostate cancer
Biomarker Discovery & Validation for Early Localized Prostate Cancer Administrative Core
This study is looking for special markers in prostate fluids and tumor tissues to help tell the difference between aggressive and non-aggressive prostate cancer, so that patients can get more personalized treatment based on their specific risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Old Dominion University NIH-funded |
| Lab location | 1 site (Norfolk, United States) |
| Project ID | NIH-10911311 on NIH RePORTER |
What this research studies
This research focuses on finding specific biological markers that can help distinguish between aggressive and non-aggressive forms of localized prostate cancer. By analyzing prostate fluids and tumor tissues, the study aims to develop and validate new tests that can accurately identify patients at risk for more severe disease. The approach combines proteogenomic techniques to enhance early detection and improve risk stratification for patients. Ultimately, this research seeks to provide better guidance for treatment decisions based on individual risk profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research are men who have recently been diagnosed with localized prostate cancer.
Not a fit: Patients with advanced prostate cancer or those who do not have localized disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and tailored treatment plans for men with localized prostate cancer.
How similar studies have performed: Previous research has shown promise in using biomarkers for cancer detection, indicating that this approach could yield significant advancements.
Where this research is happening
Norfolk, United States
- Old Dominion University — Norfolk, United States (Active)
Researchers
- Principal investigator: Semmes, Oliver John — Old Dominion University
- Study coordinator: Semmes, Oliver John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.