Identifying biomarkers and managing infections in children with atopic dermatitis colonized by S. aureus
Biomarker Identification, Viral Susceptibility and Management in S. aureus Colonized AD Patients
This study is looking at how a common bacteria called Staphylococcus aureus can make atopic dermatitis worse in kids, and it hopes to find clues that can help doctors better understand and treat this skin condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11056742 on NIH RePORTER |
What this research studies
This research investigates the role of Staphylococcus aureus in worsening atopic dermatitis (AD) in children. It aims to identify specific biomarkers that indicate susceptibility to infections and the severity of AD. The study will explore how S. aureus colonization affects the skin's barrier function and immune response, as well as the relationship between S. aureus and viral complications like eczema herpeticum. By understanding these interactions, the research seeks to improve management strategies for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are diagnosed with atopic dermatitis and are colonized by Staphylococcus aureus.
Not a fit: Patients who do not have atopic dermatitis or are not colonized by S. aureus may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options and management strategies for children suffering from atopic dermatitis and related infections.
How similar studies have performed: Previous research has indicated a strong link between S. aureus colonization and the severity of atopic dermatitis, suggesting that this approach has a solid foundation in existing literature.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Beck, Lisa Ann — University of Rochester
- Study coordinator: Beck, Lisa Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.