Identifying biological markers for early aging in people with schizophrenia
Official title: Towards Developing Biomarkers for Premature Aging in Schizophrenia
Funded at Brigham and Women's Hospital · NIH-10898917 · Data updated 2026-11-12
This study is looking at how schizophrenia might make people age faster by checking for certain proteins in their bodies, and it's for anyone with schizophrenia who wants to understand more about their health and how it relates to aging.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 3, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $130,598 |
| NIH project number | 5K99MH131850-02 |
| Project ID | NIH-10898917 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with early-stage schizophrenia who may be experiencing signs of premature aging.
✕Less likely to help
Patients with schizophrenia who are not in the early stages of the condition or those without any signs of premature aging may not benefit from this research.
What this research studies
This research investigates how schizophrenia may lead to premature aging by examining biological markers associated with this condition. The study aims to identify specific proteins that indicate aging in individuals with schizophrenia, which could help in diagnosing and monitoring their health. By analyzing data from both individuals with early schizophrenia and healthy controls, the research seeks to uncover the links between aging, cognitive function, and physical health in this population. The ultimate goal is to develop new diagnostic tools that can be used in clinical settings to better support patients.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatments for individuals with schizophrenia, enhancing their overall health and quality of life.
How similar studies have gone: Previous research has indicated a connection between schizophrenia and premature aging, but this specific approach to identifying biomarkers is relatively novel.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Seitz-Holland, Johanna — Brigham and Women's Hospital
- Study coordinator: Seitz-Holland, Johanna
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.