Identifying better tests for urinary tract infections in children
Biomarkers for Urinary Tract Infection and Pyelonephritis
This study is looking to make tests for urinary tract infections in kids more accurate, so that doctors can better tell who really has an infection and who doesn’t, helping to avoid unnecessary treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10831984 on NIH RePORTER |
What this research studies
This research aims to improve the accuracy of tests used to diagnose urinary tract infections (UTIs) in children. Current tests often miss true infections or incorrectly diagnose children without UTIs, leading to unnecessary treatments. By collecting urine samples from febrile children and analyzing them for specific biomarkers, the researchers hope to develop more reliable diagnostic tools. This study will involve a large group of children to ensure the findings are robust and applicable.
Who could benefit from this research
Good fit: Ideal candidates for this research are febrile children aged 1 month to 3 years who are suspected of having a urinary tract infection.
Not a fit: Patients who are older than 3 years or do not exhibit fever or symptoms of a urinary tract infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses of urinary tract infections in children, reducing the risk of complications and unnecessary treatments.
How similar studies have performed: Previous research has shown that developing specific biomarkers can significantly improve diagnostic accuracy in various medical conditions, suggesting a promising avenue for this study.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Shaikh, Nader — University of Pittsburgh at Pittsburgh
- Study coordinator: Shaikh, Nader
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.