Identifying beneficial bacteria for gut health

Development of a high throughput in vivo screening platform for identifying novel pro-and postbiotic bacterial strains

['FUNDING_SBIR_1'] · NEMALIFE INC. · NIH-10823009

This study is looking for new types of bacteria that can help improve gut health by testing them in a tiny worm, making it faster and easier to find effective probiotics and supplements for you.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorNEMALIFE INC. (nih funded)
Locations1 site (LUBBOCK, UNITED STATES)
Trial IDNIH-10823009 on ClinicalTrials.gov

What this research studies

This research focuses on developing a high-throughput screening platform to identify novel bacterial strains that can improve gut health. By utilizing a model organism called Caenorhabditis elegans, the study aims to efficiently test various bacterial isolates for their potential health benefits. The approach seeks to overcome the challenges of traditional methods that are slow and costly, thereby accelerating the discovery of effective probiotics and postbiotics for dietary supplementation.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing gut health issues or neurodegenerative diseases, particularly those related to Alzheimer's.

Not a fit: Patients with no gut health concerns or those not affected by neurodegenerative diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of new dietary supplements that improve gut health and potentially alleviate conditions like Alzheimer's disease and other health disorders linked to gut dysbiosis.

How similar studies have performed: Previous research has shown promise in using similar high-throughput screening methods to identify beneficial bacteria, indicating a potential for success in this novel approach.

Where this research is happening

LUBBOCK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.