Identifying beneficial bacteria for gut health
Official title: Development of a high throughput in vivo screening platform for identifying novel pro-and postbiotic bacterial strains
Funded at Nemalife INC. · NIH-10823009 · Data updated 2026-11-12
This study is looking for new types of bacteria that can help improve gut health by testing them in a tiny worm, making it faster and easier to find effective probiotics and supplements for you.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nemalife INC. NIH-funded |
| Lab location | 1 site (Lubbock, United States) |
| Project start | September 17, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $295,780 |
| NIH project number | 1R43AT012449-01A1 |
| Project ID | NIH-10823009 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing gut health issues or neurodegenerative diseases, particularly those related to Alzheimer's.
✕Less likely to help
Patients with no gut health concerns or those not affected by neurodegenerative diseases may not benefit from this research.
What this research studies
This research focuses on developing a high-throughput screening platform to identify novel bacterial strains that can improve gut health. By utilizing a model organism called Caenorhabditis elegans, the study aims to efficiently test various bacterial isolates for their potential health benefits. The approach seeks to overcome the challenges of traditional methods that are slow and costly, thereby accelerating the discovery of effective probiotics and postbiotics for dietary supplementation.
Why it matters
Potential benefit: If successful, this research could lead to the development of new dietary supplements that improve gut health and potentially alleviate conditions like Alzheimer's disease and other health disorders linked to gut dysbiosis.
How similar studies have gone: Previous research has shown promise in using similar high-throughput screening methods to identify beneficial bacteria, indicating a potential for success in this novel approach.
Where this research is happening
-
Nemalife INC.
Lubbock, United States Active
Researchers
- Principal investigator: Qureshi, Mohammed Adnan Mohammed Hanif — Nemalife INC.
- Study coordinator: Qureshi, Mohammed Adnan Mohammed Hanif
Related research
Other NIH-funded projects on the same topics.
-
Creating a platform to discover new treatments for alcohol use disorders using worms
This study is looking for new ways to help people with alcohol use problems by using tiny worms to see how certain safe, non-hallucinogenic compounds might improve treatment options.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.