Identifying Atrial Fibrillation Risk After Stroke
Official title: Risk-Guided Atrial Fibrillation Surveillance in Ischemic Stroke
Funded at Hebrew Rehabilitation Center for Aged · NIH-10900475 · Data updated 2026-11-12
This study is looking to help doctors find out which stroke patients might have hidden atrial fibrillation, so they can decide who would benefit from special heart monitoring to prevent future strokes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hebrew Rehabilitation Center for Aged NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $163,265 |
| NIH project number | 5K23HL151903-04 |
| Project ID | NIH-10900475 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have recently suffered an ischemic stroke and are at risk for developing atrial fibrillation.
✕Less likely to help
Patients who have not experienced an ischemic stroke or those with established atrial fibrillation may not benefit from this research.
What this research studies
This research focuses on improving the detection of atrial fibrillation (AF) in patients who have experienced an ischemic stroke. It aims to develop a risk estimation tool that helps identify patients most likely to have undetected AF, which can lead to recurrent strokes. By using this tool, healthcare providers can determine which patients would benefit most from long-term monitoring with implantable loop recorders (ILRs). The study will assess the acceptability and effectiveness of this risk-guided approach in clinical settings before larger trials are conducted.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of recurrent strokes in patients by ensuring timely detection and management of atrial fibrillation.
How similar studies have gone: While the approach of using risk estimation tools is innovative, similar strategies in other areas of cardiovascular health have shown promise in improving patient outcomes.
Where this research is happening
-
Hebrew Rehabilitation Center for Aged
Boston, United States Active
Researchers
- Principal investigator: Ko, Darae — Hebrew Rehabilitation Center for Aged
- Study coordinator: Ko, Darae
Related research
Other NIH-funded projects on the same topics.
-
Understanding Blood Thinners for Older Stroke Patients with Atrial Fibrillation
This project helps doctors choose the best blood thinner for older patients who have had a stroke and also have an irregular heartbeat called atrial fibrillation.
-
Improving blood flow after stroke by breaking down NETs
Aims to see if breaking down neutrophil extracellular traps (NETs) after an ischemic stroke can improve blood flow and reduce brain injury in patients.
-
EP2 blockers to protect the brain after a stroke
Aims to test brain-permeable EP2 antagonists to reduce damage after ischemic stroke and improve recovery.
-
Genetic testing to find causes of early-onset ischemic stroke
This project uses whole-exome sequencing to look for gene changes that may cause ischemic stroke in adults who had a stroke at a young age.
-
Targeted nanomedicine to protect the brain after stroke
A targeted drug-delivery approach aims to boost blood-brain barrier repair and reduce brain damage after an acute ischemic stroke in patients at risk.
-
How biological aging and blood proteins relate to thinking after a stroke
This project looks at whether measures of biological aging and patterns of blood proteins help explain which stroke survivors keep their thinking sharp and which go on to develop vascular dementia.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.