Identifying and treating specific types of breast cancer based on genetic patterns.
Developmental Research Program
This study is looking at how changes in genes affect breast cancer, especially in cases where the cancer has spread, to help find better treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10902116 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic alterations in breast cancers, particularly those related to DNA repair defects and genetic instability. By identifying specific biomarkers associated with these alterations, the research aims to develop optimal treatment strategies for patients with metastatic breast cancer. The program will support innovative projects from both new and established investigators, fostering collaboration within the research community to accelerate advancements in breast cancer diagnosis and treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with breast cancer, particularly those exhibiting homologous recombination DNA repair defects or genetic instability.
Not a fit: Patients with breast cancer who do not have identifiable genetic alterations or those with early-stage disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with specific types of breast cancer.
How similar studies have performed: Previous research has shown promise in using genetic markers to guide treatment decisions in breast cancer, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Chandarlapaty, Sarat — Sloan-Kettering Inst Can Research
- Study coordinator: Chandarlapaty, Sarat
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.