Identifying and targeting the cells that drive lung cancer growth
Defining and targeting the lung cancer progenitor cell niche using a high-resolution, multi-omics approach
This study is looking at the special cells in non-small cell lung cancer that help tumors grow and resist treatment, so we can find better ways to target them and improve therapy for patients like you.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10678892 on NIH RePORTER |
What this research studies
This research focuses on understanding the specific cells within non-small cell lung cancer (NSCLC) that contribute to tumor growth and resistance to treatment. By using advanced techniques to analyze the tumor microenvironment and the behavior of tumor-initiating cells (TICs), the researchers aim to uncover how these cells interact with their surroundings and how they can be targeted more effectively. The study involves tracking the genetic changes in these cells over time, especially in response to various treatments, to identify potential new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with non-small cell lung cancer who are undergoing treatment or have recently completed treatment.
Not a fit: Patients with other types of lung cancer or those who are not currently receiving treatment for NSCLC may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for lung cancer, improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in targeting tumor-initiating cells in various cancers, suggesting that this approach may yield significant insights and advancements in lung cancer treatment.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Charytonowicz, Daniel — Icahn School of Medicine at Mount Sinai
- Study coordinator: Charytonowicz, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.