NIH-funded research R01 grant

Identifying and supporting overdose responders to improve prevention efforts

Official title: A network-based, mixed methods study to identify and support multiple overdose responders and inform overdose prevention interventions

Funded at University of Nevada Reno · NIH-10590120 · Data updated 2026-11-12

This study is looking at how to make overdose education and naloxone distribution better for people who use drugs in Reno, Nevada, by understanding why some people help during overdoses while others don’t, so we can find ways to support those who do and improve the community's response to overdoses.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Nevada Reno
NIH-funded
Lab location1 site (Reno, United States)
Project startSeptember 30, 2022
Project endSeptember 29, 2025
Funding year2022
Award (this year)$2,034,699
NIH project number1R01DA057682-01
Project IDNIH-10590120 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who use drugs and are either actively involved in responding to overdoses or are interested in learning how to do so.

Less likely to help

Patients who do not use drugs or are not involved in overdose response may not benefit from this research.

What this research studies

This research investigates how to enhance overdose education and naloxone distribution programs for people who use drugs (PWUD). It aims to understand why some individuals actively respond to overdoses while others do not, focusing on individual characteristics, social networks, and contextual factors. By recruiting 300 PWUDs in Reno, Nevada, the study will gather both quantitative and qualitative data to identify the support needed for those who frequently respond to overdoses and to improve overall community response capabilities.

Why it matters

Potential benefit: If successful, this research could lead to more effective overdose prevention strategies and better support systems for individuals who respond to overdoses.

How similar studies have gone: Previous research has shown that community-based interventions can effectively improve overdose response rates, suggesting that this approach may yield valuable insights.

Where this research is happening

  • University of Nevada Reno
    Reno, United States
    Active

Researchers

  • Principal investigator: Wagner, Karla D. — University of Nevada Reno
  • Study coordinator: Wagner, Karla D.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.