Identifying and optimizing small molecules for reproductive health issues
CHEMICAL SCREENING AND OPTIMIZATION FACILITY - PROTEIN EXPRESSION AND/OR X-RAY CRYSTALLOGRAPHY
This study is looking for new small medicines that could help improve reproductive health issues like infertility, polycystic ovarian syndrome, and fibroids, so that patients can have better treatment options and feel healthier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sri International NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project ID | NIH-10942884 on NIH RePORTER |
What this research studies
This research focuses on discovering and refining small molecules that can address various reproductive health challenges, including infertility, polycystic ovarian syndrome, and fibroids. The approach involves using x-ray crystallography to study the structure of proteins and peptides in the presence of these small molecules, which helps in understanding their interactions and potential therapeutic effects. Patients may benefit from new treatments that improve reproductive health and address related conditions. The research aims to enhance the quality of care for individuals facing these health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing infertility, polycystic ovarian syndrome, or other reproductive health issues.
Not a fit: Patients with reproductive health issues not addressed by the specific conditions studied, such as certain genetic disorders unrelated to the identified conditions, may not benefit.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve reproductive health and fertility outcomes for patients.
How similar studies have performed: Other research has shown success in using small molecules and structural analysis to develop treatments for reproductive health issues, indicating a promising approach.
Where this research is happening
Menlo Park, United States
- Sri International — Menlo Park, United States (Active)
Researchers
- Principal investigator: Gong, Leyi — Sri International
- Study coordinator: Gong, Leyi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.