Identifying and locating lung cancer in patients with detected nodules
Detecting and locating cancer for patients with CT-detected lung nodules
This study is testing a new blood test called CancerRadar to help people with lung nodules find out if they have lung cancer or if their nodules are harmless, making it easier to catch any serious issues early without needing invasive procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10914684 on NIH RePORTER |
What this research studies
This research focuses on improving the detection of lung cancer in patients who have been identified with lung nodules through low-dose computed tomography (LDCT). It aims to develop a new system called CancerRadar, which utilizes a blood test to analyze cell-free DNA (cfDNA) for genetic and epigenetic markers associated with cancer. By combining advanced laboratory techniques and computational analysis, the study seeks to differentiate between aggressive cancers and benign lesions, ultimately providing a non-invasive method for early diagnosis. Patients will be part of clinical cohorts to validate the effectiveness of this innovative approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been identified with lung nodules through imaging and are at high risk for lung cancer, particularly current or former smokers.
Not a fit: Patients who do not have lung nodules or are not at risk for lung cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and earlier detection of lung cancer, potentially saving lives by allowing for timely treatment.
How similar studies have performed: Other research has shown promise in using cfDNA for cancer detection, indicating that this approach could be a significant advancement in the field.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Zhou, Xianghong Jasmine — University of California Los Angeles
- Study coordinator: Zhou, Xianghong Jasmine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.