Identifying aging cells using advanced imaging techniques
Single-cell label-free identification of senescence by Raman microscopy and spatial genomics
['FUNDING_OTHER'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-11178123
This study is looking at how aging cells behave using a special imaging technique that lets us see them without harming them, which could help us learn more about aging and related health issues that might benefit patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11178123 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the characteristics of aging cells, known as senescent cells, using a novel imaging technique called Raman microscopy. By employing this label-free method, researchers aim to analyze the molecular and cellular features of these cells without destroying them, allowing for a more accurate assessment of their behavior in various tissues over time. The study combines advanced imaging with machine learning to create a comprehensive profile of cell states and functions, which could lead to new insights into aging and related diseases. Patients may benefit from this research as it could enhance our understanding of cellular aging and its implications for health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing age-related health issues or conditions associated with cellular senescence.
Not a fit: Patients with acute conditions unrelated to aging or cellular senescence may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for diagnosing and treating age-related conditions by providing deeper insights into cellular aging.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques to study cellular processes, suggesting that this approach could yield valuable insights.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SO, PETER T. — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: SO, PETER T.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.