Identifying aging cells in human muscle, ovaries, and breast tissue
Mapping and validating senescent cells in human muscle, ovary and breast
['FUNDING_OTHER'] · BUCK INSTITUTE FOR RESEARCH ON AGING · NIH-10895605
This study is looking at how aging affects certain tissues in the body, like the ovaries, breast, and muscles, by identifying special markers in aging cells, and if you choose to participate, you can help by providing tissue samples to help us learn more about this process and find new ways to support healthy aging.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BUCK INSTITUTE FOR RESEARCH ON AGING (nih funded) |
| Locations | 1 site (NOVATO, UNITED STATES) |
| Trial ID | NIH-10895605 on ClinicalTrials.gov |
What this research studies
This research focuses on mapping and validating senescent cells in human tissues, specifically in the ovaries, breast, and skeletal muscle. By identifying specific markers of cellular senescence, the study aims to understand how aging affects these tissues. Patients may contribute tissue samples, which will undergo various analyses to uncover the unique characteristics of senescent cells. The findings could lead to better insights into aging and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals undergoing surgical procedures that involve the removal of ovarian, breast, or muscle tissue.
Not a fit: Patients who are not undergoing any surgical procedures or do not have access to the required tissue types may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of aging and lead to new treatments that target age-related conditions.
How similar studies have performed: Similar research has shown promise in identifying cellular senescence markers, suggesting that this approach could yield valuable insights.
Where this research is happening
NOVATO, UNITED STATES
- BUCK INSTITUTE FOR RESEARCH ON AGING — NOVATO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MELOV, SIMON — BUCK INSTITUTE FOR RESEARCH ON AGING
- Study coordinator: MELOV, SIMON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.