Identifying aggressive prostate cancer using biomarkers
Core-Biomarker Reference Laboratory
This study is looking for ways to tell the difference between slow-growing and fast-growing prostate cancer by examining urine and tissue samples, so that patients can get better diagnoses and personalized treatment based on their specific cancer type.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Old Dominion University NIH-funded |
| Lab location | 1 site (Norfolk, United States) |
| Project ID | NIH-10911314 on NIH RePORTER |
What this research studies
This research focuses on developing and validating biomarkers that can distinguish between indolent and aggressive forms of localized prostate cancer. By analyzing prostate proximal fluids and tumor tissues, the study aims to identify molecular features that indicate the risk of disease progression. The research will utilize urine-based and tissue-based assays to improve early detection and risk stratification for patients, particularly those with high-grade lesions or BRCA2 variants. Patients will benefit from more accurate diagnoses and tailored treatment options based on their specific cancer characteristics.
Who could benefit from this research
Good fit: Ideal candidates for this research are men who have been newly diagnosed with localized prostate cancer and are at risk for aggressive disease.
Not a fit: Patients with advanced prostate cancer or those who do not have localized disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate identification of aggressive prostate cancer, allowing for timely and appropriate treatment.
How similar studies have performed: Previous research has shown promise in using biomarkers for cancer detection, indicating that this approach has potential for success.
Where this research is happening
Norfolk, United States
- Old Dominion University — Norfolk, United States (Active)
Researchers
- Principal investigator: Semmes, Oliver John — Old Dominion University
- Study coordinator: Semmes, Oliver John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.