Identifying adolescents at high risk for neurocognitive disorders
Identifying Adolescents at High Risk of Neurocognitive Disorder: Development and Validation of a Composite Risk Index
This study is looking to create a helpful tool to spot young people, ages 6 to 18, who might be at risk for brain and thinking problems, especially in lower middle-income countries, including those living with or exposed to HIV, so that they can get the support they need early on.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10906484 on NIH RePORTER |
What this research studies
This research aims to develop and validate a composite risk index to identify adolescents at high risk of neurocognitive disorders, particularly in lower middle-income countries. It focuses on children aged 6 to 18 years, including those infected with HIV and those exposed to HIV but uninfected. By analyzing various risk factors such as malnutrition and immune dysfunction, the study will use advanced machine learning techniques to create a predictive model. This model will help in timely identification and intervention for at-risk children, potentially improving their cognitive outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 6 to 18 years from lower middle-income countries, particularly those who are HIV-infected or HIV-exposed uninfected.
Not a fit: Patients who are not adolescents or those from higher-income countries may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification and intervention strategies for adolescents at risk of neurocognitive disorders, ultimately improving their quality of life.
How similar studies have performed: Other research has shown success in using composite risk indices to predict health outcomes in similar populations, indicating that this approach has potential.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Ezeamama, Amara E — Michigan State University
- Study coordinator: Ezeamama, Amara E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.