Identifying a new way to diagnose MIS-C in children with fever
Diagnosis of MIS-C in febrile children
['FUNDING_OTHER'] · CHILDREN'S HOSP OF PHILADELPHIA · NIH-10732879
This study is looking for a new way to help doctors quickly identify multisystem inflammatory syndrome in children (MIS-C) after COVID-19 by testing breath, urine, and saliva samples from kids with fevers, so they can get the right care sooner.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CHILDREN'S HOSP OF PHILADELPHIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10732879 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel diagnostic method for multisystem inflammatory syndrome in children (MIS-C), which can occur after COVID-19 infection. The study aims to analyze breath, urine, and saliva samples from febrile children to identify specific biomarkers associated with MIS-C. By integrating these findings with clinical and immunological data, the researchers hope to create a reliable diagnostic tool that can differentiate MIS-C from other febrile illnesses. This approach is crucial as MIS-C can lead to severe health complications if not diagnosed promptly.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-21 years who present with fever and may be suspected of having MIS-C.
Not a fit: Patients who do not exhibit fever or are diagnosed with conditions unrelated to MIS-C may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses of MIS-C, improving treatment outcomes for affected children.
How similar studies have performed: Other research has shown promise in using biomarker analysis for diagnosing similar inflammatory conditions, suggesting potential success for this novel approach.
Where this research is happening
PHILADELPHIA, UNITED STATES
- CHILDREN'S HOSP OF PHILADELPHIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ODOM JOHN, AUDREY RAGAN — CHILDREN'S HOSP OF PHILADELPHIA
- Study coordinator: ODOM JOHN, AUDREY RAGAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.