NIH-funded research NIH-funded research

Identifying a new biomarker for painful nerve damage

Official title: Discovery and Validation of a Novel Response Biomarker Signature for Painful Peripheral Neuropathy

Funded at Lasmed, LLC · NIH-10917059 · Data updated 2026-11-12

This study is looking for a new way to measure ongoing nerve pain in people with peripheral neuropathy, so we can find better treatments that really work for you.

More Neuropathy research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLasmed, LLC
NIH-funded
Lab location1 site (Mountain View, United States)
Project startSeptember 1, 2022
Project endApril 30, 2026
Funding year2025
Award (this year)$795,734
NIH project number5R61NS122298-03
Project IDNIH-10917059 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing ongoing neuropathic pain due to conditions like diabetes, chemotherapy, or other causes.

Less likely to help

Patients with neuropathic pain that is not ongoing or those who do not have a diagnosis related to peripheral neuropathy may not benefit from this research.

What this research studies

This research aims to discover and validate a new biomarker signature that can indicate ongoing neuropathic pain in patients. By using a specialized technique to stimulate nerve fibers, the study will assess how these fibers respond to pain, which could lead to better-targeted pain therapies. The goal is to create a reliable biomarker that can help evaluate the effectiveness of treatments for painful peripheral neuropathy, a condition that significantly affects many individuals' quality of life. Patients participating in this research may undergo assessments that involve measuring their nerve responses to specific stimuli.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for patients suffering from painful peripheral neuropathy.

How similar studies have gone: Previous research has shown promise in identifying biomarkers for pain, but this specific approach is novel and has not been extensively tested.

Where this research is happening

  • Lasmed, LLC
    Mountain View, United States
    Active

Researchers

  • Principal investigator: Nemenov, Mikhail I. — Lasmed, LLC
  • Study coordinator: Nemenov, Mikhail I.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.