Identifying a blood marker to predict pain in sickle cell disease patients

The Inflammatory Index as a Biomarker for Pain in Patients with Sickle Cell Disease

['FUNDING_OTHER'] · MEDICAL COLLEGE OF WISCONSIN · NIH-10905990

This study is looking to find a blood test that can help understand and predict the pain levels in people with sickle cell disease, so that doctors can create more personalized pain management plans just for you.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorMEDICAL COLLEGE OF WISCONSIN (nih funded)
Locations1 site (MILWAUKEE, UNITED STATES)
Trial IDNIH-10905990 on ClinicalTrials.gov

What this research studies

This research aims to develop a blood biomarker that can predict and correlate with the pain experienced by patients with sickle cell disease (SCD). SCD is known for causing severe pain, but the intensity and frequency of pain can vary widely among patients. By analyzing inflammatory markers in the blood, the researchers hope to identify patterns that can help tailor pain management strategies for individuals. This approach could lead to more personalized treatment options for those suffering from this debilitating condition.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with sickle cell disease who experience varying levels of pain.

Not a fit: Patients without a diagnosis of sickle cell disease or those who do not experience pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies for patients with sickle cell disease.

How similar studies have performed: Previous research has shown promise in using biomarkers to assess pain in other conditions, suggesting potential success for this novel approach in sickle cell disease.

Where this research is happening

MILWAUKEE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.