iCAN PREVENT cancer interception program at MD Anderson
iCAN PREVENT: MD Anderson International Cancer Prevention Clinical Trials Consortium
Trying new, gentler therapies to prevent cancer in people at higher risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11222238 on NIH RePORTER |
What this research studies
MD Anderson leads an international consortium to develop and move forward less-toxic cancer prevention (interception) approaches. The team combines lab tools like single-cell genomics and spatial transcriptomics with clinical early-phase trials and strong patient advocate input. Promising strategies are tested in volunteers with biospecimen collection and clinical follow-up to check safety and biological effect. Trials and sample collection are run at MD Anderson and partnering sites to accelerate translation to the clinic.
Who could benefit from this research
Good fit: People at elevated risk for cancer—for example those with a strong family history, known genetic predisposition, precancerous lesions, or other established risk factors—who are willing to join early-phase prevention trials.
Not a fit: People who already have active cancer, who are not considered at increased risk, or who need treatments for existing cancer are unlikely to benefit from prevention-focused work.
Why it matters
Potential benefit: Could provide safer prevention treatments that reduce cancer risk while causing fewer side effects.
How similar studies have performed: Previous prevention (interception) trials, including vaccines and drugs, have shown promise but were often limited by side effects, so this program builds on that work to find safer options.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Vilar Sanchez, Eduardo — University of Tx Md Anderson Can Ctr
- Study coordinator: Vilar Sanchez, Eduardo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.