Human sample and immune testing support for severe asthma
Core B
['FUNDING_P01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-11330460
This program collects and processes blood and airway samples and runs immune cell tests from people with severe asthma to help understand how their immune system works.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-11330460 on ClinicalTrials.gov |
What this research studies
You would provide blood, sputum, or airway samples at clinic visits so the core can prepare, store, and distribute them for lab studies. The team handles initial processing, cryopreservation, and timely delivery of materials to project labs. They run advanced flow cytometry and cell sorting to profile immune cells and share results with linked research projects. The core is designed to make sure limited samples from people with severe asthma are used efficiently across multiple experiments.
Who could benefit from this research
Good fit: Ideal candidates are adults with severe, difficult-to-control asthma who can provide blood or airway samples and attend clinic visits, especially near Pittsburgh.
Not a fit: People without asthma or with only mild, well-controlled asthma are unlikely to get direct benefits from this core's work.
Why it matters
Potential benefit: If successful, this work could reveal immune cell patterns in severe asthma that point to better-targeted treatments.
How similar studies have performed: Similar biospecimen and flow-cytometry cores have identified immune cell changes in other diseases and helped guide targeted therapies, so this approach is well-established.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ORISS, TIMOTHY B — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: ORISS, TIMOTHY B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.