Human pancreas and blood bank for pancreatic cancer
Core B: Human Pancreas
Collecting and storing pancreas tissue and blood from people with pancreatic cancer or chronic pancreatitis to help researchers learn which genes and immune changes drive the disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11171454 on NIH RePORTER |
What this research studies
If you take part, Stanford will collect and store pancreas tissue, pre-cancerous lesions, and blood samples and link them to clinical and demographic information. Samples will be prepared for tests like histology, immunohistochemistry, FACS, CyTOF, single-cell RNA sequencing, and multiplex imaging (CODEX) so researchers can examine genes and immune cells in detail. The biobank supports projects that compare genetic changes such as KRAS mutations and tumor suppressor alterations across cancer, precancer, and chronic pancreatitis samples. By sharing samples, patients enable direct comparisons between findings in mouse models and human disease that can guide future diagnostics and treatments.
Who could benefit from this research
Good fit: People with pancreatic ductal adenocarcinoma (PDAC), pre-cancerous pancreatic lesions, or chronic pancreatitis who can provide tissue or blood samples and share their medical information are ideal candidates.
Not a fit: People without pancreatic disease, or those unable or unwilling to donate tissue or blood or share medical records, are unlikely to be eligible or gain direct benefit.
Why it matters
Potential benefit: Could speed up discoveries about genetic drivers and immune targets that lead to earlier diagnosis or better treatments for pancreatic cancer.
How similar studies have performed: Other human tissue banks and molecular profiling efforts have successfully revealed cancer drivers and biomarkers, though turning those findings into new pancreatic cancer treatments remains difficult.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Park, Walter Gwang-Up — Stanford University
- Study coordinator: Park, Walter Gwang-Up
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.